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Heparin Enoxaparin Sodium Injection Supplier


Heparin Enoxaparin Sodium Injection
Business Type Manufacturer, Exporter, Supplier
Brand Name GJ
Dose 40mg per 0.4ml PFS
Packaging Size 1 Prefilled Syringe
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Preferred Buyer From

Location All Countries Except India

Product Details

Packaging Type 1 Prefilled Syringe
Best Before 6 months from Manufacture date
Form Of Medicine Injection
Storage Store in cool and dry place

Warning:
Epidural or spinal hematomas may occur in patients who are anticoagulated with low molecular weight heparins (LMWH) or heparinoids and are receiving neuraxial anesthesia or undergoing spinal puncture. These hematomas may result in long-term or permanent paralysis. Consider these risks when scheduling patients for spinal procedures. Factors that can increase the risk of developing epidural or spinal hematomas in these patients include:

  • Use of indwelling epidural catheters
  • Concomitant use of other drugs that affect hemostasis, such as non-steroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, other anticoagulants.
  • A history of traumatic or repeated epidural or spinal punctures
  • A history of spinal deformity or spinal surgery


Description: Lovenox is a sterile aqueous solution containing enoxaparin sodium, a low molecular weight heparin. The pH of the injection is 5.5 to 7.5. Enoxaparin sodium is obtained by alkaline depolymerization of heparin benzyl ester derived from porcine intestinal mucosa. Its structure is characterized by a 2-O-sulfo-4-enepyranosuronic acid group at the non-reducing end and a 2-N,6-O-disulfo-D-glucosamine at the reducing end of the chain. About 20% (ranging between 15% and 25%) of the enoxaparin structure contains an 1,6 anhydro derivative on the reducing end of the polysaccharide chain. The drug substance is the sodium salt. The average molecular weight is about 4500 daltons.

Indications and Dosage:
Indications

Prophylaxis of Deep Vein Thrombosis
Lovenox® is indicated for the prophylaxis of deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE):

  • in patients undergoing abdominal surgery who are at risk for thromboembolic complications [see Clinical Studies].
  • in patients undergoing hip replacement surgery, during and following hospitalization.
  • in patients undergoing knee replacement surgery.
  • in medical patients who are at risk for thromboembolic complications due to severely restricted mobility during acute illness.


Storage

  • Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F) [see USP Controlled Room Temperature].
  • Do not store the multiple-dose vials for more than 28 days after the first use.
  • Keep out of the reach of children.
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